Discoveries in the biomedical sciences and innovations in clinical medicine have led to significant victories in our longstanding war against disease and suffering. With the mapping of the entire human genome, we are now closer to the understanding of the mechanisms of life, aging, illness and death, opening up exciting new opportunities for advances in therapeutics. Novel insights in the life science and technological advances in medicine will result in better health and an improved quality of life for the human race in the new century.
for his pioneering development and use of cryogenic-electron tomography (cryo-ET), an imaging technique that enables three-dimensional visualisation of biological samples, including proteins, macromolecular complexes, and cellular compartments as they exist in their natural cellular settings.
Prizes in Life Science and Medicine have been awarded to one laureate only
Prizes in Life Science and Medicine have been shared by two laureates
Prizes in Life Science and Medicine have been shared by three laureates
for their discovery of molecular mechanisms underlying circadian rhythms.
for their contributions to the understanding of the molecular mechanism of protein folding. Proper protein folding is essential for many cellular functions.
for their discovery of the molecular mechanism of innate immunity, the first line of defense against pathogens.
for his seminal discoveries of molecular mechanisms by which the skin senses painful stimuli and temperature and produces pain hypersensitivity.
for their work leading to the discovery of leptin, a hormone that regulates food intake and body weight
for their recent pivotal innovations in reversing the process of cell differentiation in mammals, a phenomenon which advances our knowledge of developmental biology and holds great promise for the treatment of human diseases and improvements in agriculture practices.